However, companies generally like to keep it at 5% for the convenience of formulation, because it adds challenge to dissolve more material and keep the product stable. One study conducted on stemoxydine examined its efficacy in treating male pattern hair loss. I didn't expect much effect at all. Answer: Hi, Madeleine. I would like to begin using products (LOreal, Vichy, etc) for hair regrowth on bald spots, however, I am pregnant.What are the effects of these products on my unborn child and future fertility please?I could not find any studies regarding Stemoxydine on fertility. This makes it difficult to choose the right products. Many of them have completely different key ingredients. It is difficult to determine which treatment is better, as there is limited scientific evidence comparing stemoxydine and minoxidil. This makes it hard to form an opinion so taking Stemoxydine would be at your own risk. Hairline Lowering Surgery: What Is It? All rights reserved. Welcome to The Hair Loss Show. In the United States alone, approximately 56 million people experience some form of hair loss, according to the International Society of Hair Restoration Surgery (ISHRS). L'Oreal used to have hair growth product based on Aminexil. 16% minoxidil, 15% minoxidil, 10 minoxidil, 5% minoxidil, 3% minoxidil, one stop for custom minoxidil products. It offers a unique mechanism of action compared to other hair loss treatments, such as. If it works, it most likely due to the presence of minoxidil in the same product. For that reason strengthening the reason to apply it twice a day imo. is topical, there are quite few barriers to get through before a topical Participants were assigned to receive either a placebo or stemoxydine applied topically to the scalp once a day for three months. Based on our experinces, 90% of the people who are allergic to minoxidil products are due to Propylene glycol (PPG) or alcohol. It has the potential to provide a safe and effective solution for those seeking to combat. I am indeed still using minoxidil and stemox combo on my stubble. We do not believe either Stemoxyldine or Aminexil comes close to the effectiveness of minoxidil in stimulating hair regrowth. I didn't expect much effect at all. Countering my increasing bias towards oral Minoxidil, a widely cited 2021 systemic review via meta-analysis found the following efficacy ranking for hair loss medications: 0.5 mg/d of oral dutasteride. It affects some enzyme activities and creates ahypoxia environment to help stimulate hair regrowth. less*, without hair) is Reddit's most popular community for males and females coping with hair loss. While stemoxydine has a unique mechanism of action, minoxidil has more extensive research and is FDA-approved. It can be included in various hair care products such as shampoos, conditioners, and serums. Does it mean Stemoxydine works better than Aminexil? After that I apply around 1,5 ml of stemoxydine on my hairline. This three-step regimen, consisting of a serum, conditioner, and shampoo, effectively stimulates healthy hair growth and reduces hair loss without the use of harmful chemicals. L'Oreal claims that Stemoxydine help create the hypoxia environment and awaken dormant stem cells and produces increase numbers of follicles and also increased density. Scandinavian Biolabs offers a risk-free 150-day money-back guarantee, ensuring customer satisfaction with guaranteed results. Question: Can stemoxydine treat hair loss? P.S. I want to use 0.5 mg instead of 1mg finasteride in each application. We ship to UK, EU, North America, Canada, Japan, Australia and almost every country in the world. 5 mg/d of oral finasteride. I'll explain the mechanism of action and how it works. Stemoxydine is a great hair growth stimulant with no side effects. Laser therapy is thought to work by increasing blood flow to the hair follicles, which in turn can improve the health and growth of hair. Laser therapy may work best when used with other hair loss treatments. Now Aminexil is all replaced by stemoxydine in all of L'Oreal products. So, Stemoxydine is supposed to create this low-oxygen environment to create longer and denser hair for people suffering from hair loss. Customers should use the product every day for three months for optimal results, but they should notice an improvement in hair density in as little as 6 weeks. I would say this is pretty safe stuff for me and generally for the most of the people, but it doesn't mean it would be side free for you, just keep it in mind. It was soon found to stimulate hair growth. To promote this process, L'Oral's researchers have developed Stemoxydine, an active ingredient that imitates the optimal environment of stem cells in hair follicles, revitalizing hair that has become dormant. All rights reserved. The treatment is designed to promote hair regrowth by mimicking hypoxic conditions in stem cells [4]. I saw a similar, but weaker correlation between those with substantial chest hair and scalp hair loss. Having said so, the side effects of stemoxydine product are sure to be different from those of minoxidil. Is Stemoxydine suitable as a treatment for hair loss or baldness? But there is not enough evidence for us to recommend it, yet. Is it true? Can propylene glycol (in Minoxidil) damage my brain when applied to my scalp? Aminexil had been marketed by L"Oreal for more than 15 years. Male Hair Loss The kenogen phase is the period after hair shedding and before the hair regrows. L'Oreal claimed that Aminexil help prevent perifollicular fibrosis (scarring of the hair follicles) and therefore help treatment for hair loss. 21 male shedding about 20 hair in shower, is that normal? When the solution is put on the scalp, some people may feel irritation, dryness, itching, redness, or a burning sensation. While its efficacy is still being researched, it offers several benefits, including activating dormant hair follicles and increasing hair density by inducing the anagen phase of the hair growth cycle. Can I mix the stemoxidine solution with the minoxidil solution? New comments cannot be posted and votes cannot be cast. If youre experiencing a medical issue, please contact a healthcare professional or dial 911 immediately. Because of that I am not able to make before and after photo at the moment, so you have to just believe me. On the Stemoxydine product directions it says to use for 3 months. Hi , can I shift from minoxidil5% + aminexil 1.5%to only minoxidil 5% , since minoxidil with aminexil is not sold anymore . Our body is a very precise machine, if some of the enzyme activities are affected, it is very unlikely that it does not have any side effects. Vikram JayaprakashLevel 2, 148 Glenferrie Road,Malvern, Vic 3144, Australia0395761465 https://atlantismedical.com.au/IG: @atlantismedical.melbourneenquiries@atlantismedical.com.auDr. Stemoxydine is believed to work by creating a low-oxygen environment, which has been shown to stimulate hair growth. Can Apple Stem Cell Products Treat Thinning Hair? With minoxidil 2x daily, and now I recently added the Garnier Fructis with Stemoxydine, there isn't a single hour that I don't have some kind of goop slathered on my scalp. Stemoxydine is a patented molecule by L'Oreal for hair loss treatment (see more detailed information about Stemoxydine here). Stemoxydine can activate dormant hair follicles and increase hair density by inducing the anagen phase of the hair growth cycle, resulting in thicker hair. If your hair loss is extreme, it might be time to consider a hair transplant instead. Another key thing to consider is that Stemoxydine is an ingredient in many cosmetic hair thickening products. 1. Therefore, as it has not achieved these important authorisations for the function of treating thinning hair in men or women with genetic hairloss, it cannot be deemed a 'hair loss treatment'. Minoxidil is one of the most popular hair loss treatments that has been used to effectively promote hair regrowth in as little as 16 weeks [8]. Minoxidil is a medication that is commonly used as a topical solution to treat hair loss in both men and women. using Stemoxydine in the morning and Minoxidil at night or Stemoxydine between the two doses of Minoxidil. I would even say that in those 3 weeks Stemoxydine gave me more growth than 1 years of minoxidil in total, but I think I was just always weak minoxidil responder. Book your free consultation with Wimpole Clinic today. Aminexil is dead now. Copyright Wimpole Clinic - All Rights Reserved -, This is mainly because there still isnt really a definitive answer as to what causes pattern hair loss [3]. PRP and Progesterone have been clinically proven to be a safe and effective solution to hair loss. 15% minoxidil). If you are allergic to minoxidil itself, you can give Stemoxydine a try. It dries out much quicker than liquid minoxidil, but less quickly than foam minoxidil. Did you know that hair loss is a common problem that affects millions of people worldwide? This product is not as innocent as it is claimed to be. If you are interested in knowing more about minoxidil, you can read our blog: Minoxidil Frequently Asked QuestionsandProfessional Review. Read the blog ", We do not believe either Stemoxyldine or Aminexil comes close to the effectiveness of minoxidil in stimulating hair regrowth. Stemoxydine is one of the ingredients in their product Kerastase Densifique. It was first used as an oral drug to lower blood pressure. In this episode, we will be covering Stemoxydine. For Densitive, the treatment is contraindicated if you have allergies to any of the ingredients (taurine, green tea, grape seed oil, zinc). During the study, subjects applied stemoxydine 5% solution (aka, stemoxydine 5) once a day (6ml). While we do connect people with vetted, board-certified doctors, we dont provide medical consultations, diagnosis, or advice. Dr Amy Revene M.B.B.S. Instead, it might be because the new chemical gives them the exclusive ownership of a formulation so nobody else can copy it, or it might be due to regulation related reasons. | I'm a diffuse thinner, not doing anything to treat my hair loss at the moment. This would require a series of treatments, and usually after a monthly injection for 4-5 months should show improvement. This can lead to a decreased hair density and contribute to the symptomatic thinning hair. The contents of this Youtube channel, such as videos, text, graphics, images and other material are intended for entertainment, information and educational purposes only and are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Stemoxydine is a topical hair loss treatment thats classified as a prolyl-4-hydroxylase (P4H) inhibitor. The study was conducted in a double blind vs placebo study consisting of 101 men between 18 and 55 years old. Furthermore, I can't wait to see more results (if any) in upcoming weeks. If you are worried about hair loss you can arrange a free consultation with a hair loss expert or complete our Online Consultation from anywhere in the world for home-use treatment. I would reccomend getting a vehicle like stemoxydine or k&b and that way you could pour the topical finasteride In another solution to spread it more evenly and adjust the doses if you like. Update: January 11, 2023 Dr. Joyce Davis from New York just concluded that the use of low-dose oral Minoxidil for hair loss was the biggest news in dermatology in 2023. Having said so, the side effects of stemoxydine product are sure to be different from those of minoxidil. Archived post. It's literally the reason why people try it over oral fin..hoping that they won't get side effects. (FUT), both of which we offer at Wimpole Clinic. Over a series of treatments . Start off with a no-obligation consultation. Stemoxydine is typically applied to the scalp daily for three months, with noticeable improvements in hair density within six weeks. Stemoxydine is a patented molecule by L'Oreal for hair loss treatment (see more detailed information about Stemoxydine here). However, it is important to note that stemoxydine may not be suitable for everyone and that several other effective treatments are available, such as Scandinavian Biolabs Hair Growth Routine, minoxidil, finasteride, hair transplant surgery, laser therapy, and nutritional supplements. Https://www . For example, when you toss a coin, you expect to see the tail 50% of the times. Is there a side effect of using higher conc of Minoxidil? Interestingly, usage directions also state for some of these formulations that it should be applied to the lengths of the hair, which are dead, as well as the scalp. How do you make the propylene glycol free minoxidil? Is it really true? Lowering DHT level is the main approach in popular hair loss products such as Lipogaine for Men and Maxogen-S. Other than L'Oreal reported clinical study that showed an increase of 4% in hair density on the patients treated with stemoxydine for 3 months, there aren't many stemoxydine users who have shown their before and after pictures. 5 mg/d of oral minoxidil. After a couple of months those hairs began to getting thicker, darker and stronger, and they are terminal at the moment. Patients with androgenetic alopecia may have suboptimal hair follicle growth cycle. Big 3 + 1? Two of the most hair transplant treatments that men and women are choosing at the moment are Follicular Unit Extraction (FUE) and Follicular Unit Transplantation (FUT), both of which we offer at Wimpole Clinic. Thus it is worth considering, You may also consider minoxidil product with low propylene glycol concentration such as, hi there, can I use stemoxydine solution to dilute, If you want to lower the finasteride concentration of Essengnen-F, it is best to use. 10% are due to minoxidil itself. Using a topical finasteride only (without minoxidil) can also help get ride of the issue. Before using stemoxydine, people who have had allergic reactions or other health problems in the past should talk to their doctor. If you want to lower the finasteride concentration of Essengnen-F, it is best to use PG Solvent. Thank you for submitting your questions. Did anybody here also get great results from Stemoxydine? If one used to lose 10 and now loses 20, its abnormal. Why are so many hair loss products at 5%? The formula contains the key ingredient Capilia Longa, a plant-powered ingredient that has been clinically proven to increase hair density by over 23% and reduce hair loss in 93.3% of volunteers. Here we are going to briefly examine these two ingredients in comparison with the gold standard Minoxidil. Alcohol Denatured, Water, Diethyllutidinate, Fragrance, Niancinamide, Sugar Cane Extract / Saccharum Officinarum Extract, Camellia Sinensis Leaf Extract, Benzyl Alcohol, Linalool, 2-Oleamido-1,3-Octadecenediol, Pyrus Malus Extract / Apple Fruit Extract, Pyridoxine HCI, Geraniol, Citric Acid, Citrus Medica Limonum Peel Extract / Lemon Peel Extract, Hexyl Cinanamal, Amyl Cinnamal. Stemoxydine is a hair loss treatment that has gained popularity due to its potential to stimulate hair growth. We ship to Austria, Italy, Belgium, Latvia, Bulgaria, japan, israel, Lithuania, Croatia, Luxembourg, Cyprus, Malta, Czechia, japan, new zealand, Netherlands, Denmark, Poland, Estonia, Portugal, Finland, Romania, France, Slovakia, Germany, Slovenia, Greece, Spain, Hungary, Sweden, norway, Ireland. Although there are many treatments that you can undergo to prevent or stop hair loss, one of the newer treatments that are gaining popularity is Stemoxydine. This is a dose-dependent hairloss solution which encourages localised, accelerated hair growth. Clinical studies have shown that higher minoxidil concentration is more effective than lower minoxidil concentration in stimulating hair regrowth. | These are the medical regulatory authorities charged with thoroughly reviewing each medication before it is allowed to be prescribed or otherwise made available to the public. Answer: PRP and Progesteron Injections for Hair Regrowth . 23 comments There are numerous products on the market intended for hair loss treatment. Topical Spironolactone 5% For hair loss and acne, Max Roller System For Hair Loss Treatment & Skin Rejuvenation. This procedure is typically recommended for individuals with significant hair loss or thinning and requires a consultation with a hair transplant specialist to determine if the person is a good candidate for the procedure. Topical Finasteride | All You Need To Know, Minoxidil product without Propylene Glycol, Stemoxydine 5 vs Minoxidil vs Aminexil Review | Hair Loss Ingredients, Minoxidil Frequently Asked Questions & Minoxidil Review. However, if you haven't used any of them, it is probably wise to use minoxidil only. The surgery can take several hours and may involve either follicular unit transplantation (FUT) or follicular unit extraction (FUE) techniques. Read this: The 12 Best Natural and Drug Hair Transplant Alternatives. Are There Better Options? While the therapy has shown some promise in clinical studies, more research is needed to fully understand its effectiveness and long-term safety. It is typically taken in the form of a tablet, usually once a day. However, its effectiveness may vary depending on individual factors. Although some smaller-scale trials have yielded positive results, they need to be recreated on a much larger scale to prove Stemoxydine is a beneficial hair loss treatment. These stem cells near the skins surface are responsible for creating new hair. Furthermore, as it is not a drug, it has not been licensed by the MHRA in the UK nor approved by the FDA in the USA for the purpose of treating genetic hair loss. So it is worthy trying a stemoxydine based product if you are allergic to minoxidil itself. It sounds like a heavy regime, but it cost me literally just a couple of minutes every day as it became a part of my routine. So it is worthy trying a stemoxydine based product if you are allergic to minoxidil itself. In this episode, we will be covering Stemoxydine. This makes it difficult to choose the right products. Stemoxydine's IUPAC name is Diethyl pyridine-2,4-dicarboxylate ( see its molecular modeling image blow). Below you can see the different mechanisms of actions between Minoxidil and Stemoxydine. Big 3 + 1? It was used prior to Stemoxydine but recently got ditched by L'Oreal. It is a topical solution designed to mimic hypoxic conditions in stem cells by inhibiting prolyl-4-hydroxylase. This mechanism of action activates dormant hair follicles and increases hair density by inducing the anagen phase of the hair follicle growth cycle. Hair loss Experiences Forum Welcome to the Hair loss Experiences forum. minoxidil5% + aminexil 1.5%to only minoxidil 5%. I have used Lipogaine for Men for 5 years, if I switch to Dualgen-15, will I experience any hair loss? The Belgravia Centre9 Longmoore StreetLondonSW1V 1JH, @ Belgravia Centre If any side effects happen, people should stop using it and talk to their doctor or a specialist in hair loss. If I had to put a figure to it, I would guess that 75 percent of men with excessive body hair (especially hairy backs) tend to be balding severely. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. people tolerate Minoxidil quite well. It was soon found to stimulate hair growth. Although this may not be the perfect treatment for those who are suffering from baldness or hair loss, there are plenty of other alternative hair loss treatments that you can explore. Hairline: After evening shower I apply minoxidil on my hairline, and after it dries out I give it like an hour/couple of hours to get properly absorbed into my skin. We do not know. Vitamin D is also important for healthy hair because it helps control when hair grows and falls out. If you think that a hair transplant could be the perfect solution to your hair loss problems, or you just need some professional advice to figure out what kind of treatment is best for your hair, you can get easily get advice from our experts at, https://www.ncbi.nlm.nih.gov/books/NBK278957/, https://www.health.harvard.edu/staying-healthy/treating-female-pattern-hair-loss, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174066/, https://www.karger.com/Article/Fulltext/493587, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158624/, https://pubmed.ncbi.nlm.nih.gov/17761356/, Awarded Hair Transplant Clinic of the Year 2023, Minoxidil is one of the most popular hair loss treatments, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158624, https://pubmed.ncbi.nlm.nih.gov/20203417/. This is the category we would suggest stemoxydine products belong in as they are rather an adjunct to proven medication, not an alternative. Read this: The 7 Best Natural and Drug Alternatives To Minoxidil. It is important to use it as directed and avoid using it on broken or irritated skin. It works by blocking the production of dihydrotestosterone (DHT), a hormone that contributes to hair loss. A clinical trial carried out in 2014 on men between 18 and 55 years with moderate Male Pattern Hair Loss, found that topical applications of the prolyl 4 hydroxylase competitive inhibitor, Stemoxydine, could shorten this period of the hair cycle. Researchers concluded in their findings, published in the International Journal of Trichology, that the drug "could act as a hair kenogen phase shortener, leading to an increase in visible scalp hair density.". We very often received questions from our customers asking our thoughts on Stemoxydine and Aminexil. Monday to Friday: 9 AM - 10 PM CESTSaturday & Sunday : 1 PM - 9 PM CESTcontact@scandinavianbiolabs.comTelephone:+45 70 60 57 08[ 9 AM - 12 PM, Monday - Friday ]. Speak to us about hair transplants or hair loss treatments, and start your journey to getting your full head of hair back again. Receding Hairline: Whats The Difference. All subjects returned to nuormal HPA axis function at follow-up 4 weeks after the end of treatment. Get ready to discover the fascinating scientific properties of stemoxydine and how it can effectively address the problem of hair loss. Availability over-the-counter in most countries, Dont affect hormones e.g DHT, Testosterone or enzymes (5-alpha reductase), Only effective as long as you use them continuously, Mechanism of hair growth stimulation is likely to be more complex and hasnt been fully established yet, Doesnt come in a foam version (liquid only), Available as Serioxyl (Loreal) or Cerafill, 3-month supply is slightly more expensive than 3-month supply of Minoxidil, Shortens the Kenogen phase (phase of inactivity between the old Telogen and new Anagen hair follicle phase), Not FDA approved for treating androgenetic alopecia, Most of the clinical data on Stemoxydine comes from Loreal (company bias), Grows less hair than Minoxidil (less effective), Side effect profile is milder compared to Minoxidil, Available by dozens of brands (due to expired patent), 3-month supply is cheaper than 3-month supply of Stemoxydine, Prolongs the Anagenphase and shortens Telogen phase, Causes premature shock loss (during the first months of use), Clinical data on Minoxidil comes from various sources (low company bias), FDA approved for treating androgenetic alopecia, The liquid version takes longer to dry compared to Stemoxydine, Grows more hair than Stemoxydine (more effective), Side effect profile of Minoxidil can be higher as it is known for being an anti-hypertensive vasodilator (in its oral form e.g Loniten), Minoxidil tends to irritate the scalp more compared to Stemoxydine, because of Propylene Glycol. It is typically used twice daily, with visible results seen after about four months of consistent use. Stemoxydine is a topical hair loss treatment that's classified as a prolyl-4-hydroxylase (P4H) inhibitor. Reddit, Inc. 2023. However, like any medication, there is a risk of potential side effects. We'll delve into its numerous benefits, potential risks, and explore some alternative treatments to provide you with a comprehensive overview. Minoxidil Minoxidil is applied directly to the scalp and is absorbed through the skin. It would be interesting to see the precise trial data hair care brands promoting the use of Stemoxydine to thicken hair. This can lead to a decreased hair density and contribute to the symptomatic thinning hair. Hypoxia, or oxygen deprivation, has been shown to stimulate hair growth by inducing the anagen phase of the hair growth cycle [5]. What is the Best Buzz Cut for a Receding Hairline? graduated from the University of Sharjah in the United Arab Emirates. If it works, it most likely due to the presence of minoxidil in the same product. On the positive side, it smells like a fancy salon scent, and to quote another user to end this post; ''Dude, Stemoxydine just smells so fucking good, my god. Do as75.187others and discover how to boost your hair health with endless inspiration and exclusive content. From vitamin infusion therapy to prescription and over-the-counter drugs like Minoxidil and Finasteride, there are quite a few options but, wed always recommend talking to a specialist before trying anything out. My attention was immediately attracted to Stemoxydine. After looking at all the information on Stemoxydine, we think that it could be potentially beneficial. What exactly is stemoxydine? : Minoxidil has been proven to regrow hair on the top of the head. As such, researchers concluded in their findings, published in the International Journal of Trichology, that the drug "could act as a hair kenogen phase shortener, leading to an increase in visible scalp hair density.". Read this: 6 Most Effective Alternatives To Finasteride. 2023 - www.belgraviacentre.com - All Rights Reserved. Already as of day two, a very persistant headache, concentration loss and feverish feeling. It is important to carefully consider these factors before undergoing the procedure. I had begun with a new job at a coronavirus diagnostic laboratory, due to the nature of my work I was obligated to be clean shaved/light stubble for safety reasons at my workplace. There are people who are allergic to minoxidil itself too. Before taking any medications or supplements consult with a physician. Many people (including those doctors selling it) claim that it only lowers DHT levels in the blood by about 1/18th but that it lowers DHT levels in the scalp/follicles by much more. Why can't they be at 2% or 20%? 5% topical minoxidil.'. Another point I would like to point out is even if Stemoxydine works as what L'Oreal claims, it does nothing to address the detrimental effect of DHT (dihydrotestoserone) in the blood stream. By mimicking this low-oxygen environment, stemoxydine activates dormant hair follicles and increases hair density by inducing the anagen phase of the hair growth cycle. The clinical data of cosmetic products do not face high scrutity as those of OTC drugs (such as minoxidil). There were 101 subjects in the L'Oreal's clinical study, which means there was only 50 subjects who were given the stemoxydine and 50 who were given pacebo. There is no organization to approve cosmetic products, and nobody to examine its clinic study and safety information. Also It works as a great after shave as well due to the high percentage of alcohol, not wise though due to the increased absorption, but I still use it anyway. Please note that ~ 90% of people who are allergic to minoxidil products are actually allergic to propylene glycol not minoxidil itself. Telogen phase can never be avoided and belongs to a natural regeneration process of the hair follicle. Research shows that DHT causes hair follicles to miniatuirize and trigger hair loss.
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